Attenuation of Alzheimer’s brain pathology in 5XFAD mice by PTH1-34, a peptide of parathyroid hormone

Abstract Background Alzheimer’s disease (AD) and osteoporosis are two distinct diseases but often occur in the same patient. Their relationship remains poorly understood. Studies using Tg2576 AD animal model demonstrate bone deficits, which precede the brain phenotypes by several months, arguing for...

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主要な著者:	Li Chen, Lei Xiong, Lingling Yao, Jinxiu Pan, Emily Arzola, Xiaojuan Zhu, Lin Mei, Wen-Cheng Xiong
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2023-03-01
シリーズ:	Alzheimer’s Research & Therapy
主題:	Alzheimer’s disease PTH Aβ Neuroinflammation Astrocytes
オンライン･アクセス:	https://doi.org/10.1186/s13195-023-01202-z
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