Attenuation of Alzheimer’s brain pathology in 5XFAD mice by PTH1-34, a peptide of parathyroid hormone

Abstract Background Alzheimer’s disease (AD) and osteoporosis are two distinct diseases but often occur in the same patient. Their relationship remains poorly understood. Studies using Tg2576 AD animal model demonstrate bone deficits, which precede the brain phenotypes by several months, arguing for...

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Detalhes bibliográficos

Principais autores:	Li Chen, Lei Xiong, Lingling Yao, Jinxiu Pan, Emily Arzola, Xiaojuan Zhu, Lin Mei, Wen-Cheng Xiong
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-03-01
coleção:	Alzheimer’s Research & Therapy
Assuntos:	Alzheimer’s disease PTH Aβ Neuroinflammation Astrocytes
Acesso em linha:	https://doi.org/10.1186/s13195-023-01202-z
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