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Genetic trans-complementation establishes a new model for influenza virus RNA transcription and replication.

The influenza A viruses genome comprises eight single-stranded RNA segments of negative polarity. Each one is included in a ribonucleoprotein particle (vRNP) containing the polymerase complex and a number of nucleoprotein (NP) monomers. Viral RNA replication proceeds by formation of a complementary...

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Autors principals: Núria Jorba, Rocío Coloma, Juan Ortín
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2009-05-01
Col·lecció:PLoS Pathogens
Accés en línia:http://europepmc.org/articles/PMC2682650?pdf=render
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