RhoA-GTPase Modulates Neurite Outgrowth by Regulating the Expression of Spastin and p60-Katanin

RhoA-GTPase (RhoA) is widely regarded as a key molecular switch to inhibit neurite outgrowth by rigidifying the actin cytoskeleton. However, during neurite outgrowth, whether and how microtubule dynamics are regulated by RhoA remains to be elucidated. Herein, CT04 and Y27632 were used to inactivate...

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Detalles Bibliográficos

Principais autores:	Dandan Tan, Haowen Zhang, Junyao Deng, Jingmin Liu, Jinkun Wen, Lixia Li, Xianghai Wang, Mengjie Pan, Xiaofang Hu, Jiasong Guo
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2020-01-01
Series:	Cells
Assuntos:	neurite outgrowth rhoa signaling pathway spastin p60-katanin microtubule-severing proteins glu-tubulin
Acceso en liña:	https://www.mdpi.com/2073-4409/9/1/230
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