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Changes in mitochondrial thymidine metabolism and mtDNA copy number during induced pluripotency

Abstract Somatic cell reprogramming into human induced pluripotent stem cells entails significant intracellular changes, including modifications in mitochondrial metabolism and a decrease in mitochondrial DNA copy number. However, the mechanisms underlying this decrease in mitochondrial DNA copy num...

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主要な著者: Hyun Kyu Kim, Yena Song, Minji Kye, Byeongho Yu, Hyung Kyu Choi, Sung-Hwan Moon, Man Ryul Lee
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2025-06-01
シリーズ:Experimental and Molecular Medicine
オンライン・アクセス:https://doi.org/10.1038/s12276-025-01476-3
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