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N-oleoyl glycine and N-oleoyl alanine attenuate alcohol self-administration and preference in mice

Abstract The endocannabinoid system (ECS) plays a key modulatory role during synaptic plasticity and homeostatic processes in the brain and has an important role in the neurobiological processes underlying drug addiction. We have previously shown that an elevated ECS response to psychostimulant (coc...

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Autors principals: Samah Shahen-Zoabi, Reem Smoum, Alexey Bingor, Etty Grad, Alina Nemirovski, Tawfeeq Shekh-Ahmad, Raphael Mechoulam, Rami Yaka
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2023-07-01
Col·lecció:Translational Psychiatry
Accés en línia:https://doi.org/10.1038/s41398-023-02574-4
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