Spontaneous and Naloxone-Precipitated Withdrawal Behaviors From Chronic Opiates are Accompanied by Changes in N-Oleoylglycine and N-Oleoylalanine Levels in the Brain and Ameliorated by Treatment With These Mediators

Rationale: The endocannabinoidome mediators, N-Oleoylglycine (OlGly) and N-Oleoylalanine (OlAla), have been shown to reduce acute naloxone-precipitated morphine withdrawal affective and somatic responses.Objectives: To determine the role and mechanism of action of OlGly and OlAla in withdrawal respo...

Ful tanımlama

Detaylı Bibliyografya

Asıl Yazarlar:	Samantha M. Ayoub, Fabiana Piscitelli, Cristoforo Silvestri, Cheryl L. Limebeer, Erin M. Rock, Reem Smoum, Mathew Farag, Hannah de Almeida, Megan T. Sullivan, Sébastien Lacroix, Besma Boubertakh, Nayudu Nallabelli, Aron H Lichtman, Francesco Leri, Raphael Mechoulam, Vincenzo Di Marzo, Linda A. Parker
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Frontiers Media S.A. 2021-09-01
Seri Bilgileri:	Frontiers in Pharmacology
Konular:	oleoyl alanine oleoyl glycine opiate withdrawal endocannabinoidome somatic withdrawal heroin self-administration
Online Erişim:	https://www.frontiersin.org/articles/10.3389/fphar.2021.706703/full
Etiketler:	Etiketle Etiket eklenmemiş, İlk siz ekleyin!