Dexmedetomidine attenuates spinal cord ischemia–reperfusion injury through both anti-inflammation and anti-apoptosis mechanisms in rabbits

Abstract Background Dexmedetomidine (Dex) can improve neuronal viability and protect the spinal cord from ischemia–reperfusion (I/R) injury, but the underlying mechanisms are not fully understood. This study investigated the effects of dexmedetomidine on the toll-like receptor 4 (TLR4)-mediated nucl...

Whakaahuatanga katoa

Ngā taipitopito rārangi puna kōrero

Ngā kaituhi matua:	Zhixiang Sun, Tianyun Zhao, Shaojun Lv, Ying Gao, Joe Masters, Hao Weng
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	BMC 2018-07-01
Rangatū:	Journal of Translational Medicine
Ngā marau:	Dexmedetomidine Spinal cord ischemia–reperfusion injury Neuroprotection Apoptosis Inflammatory responses
Urunga tuihono:	http://link.springer.com/article/10.1186/s12967-018-1583-7
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!