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Understanding and drugging RAS: 40 years to break the tip of the iceberg

Several cancers and rare genetic diseases are caused by dysregulation in the RAS signaling pathway. RAS proteins serve as molecular switches that regulate pathways involved in cellular growth, differentiation and survival. These pathways have been an intense area of investigation for four decades, s...

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Principais autores: Donita C. Brady, Julija Hmeljak, Arvin C. Dar
פורמט: Artigo
שפה:Inglês
יצא לאור: The Company of Biologists 2022-02-01
סדרה:Disease Models & Mechanisms
נושאים:
גישה מקוונת:http://dmm.biologists.org/content/15/2/dmm049519
תגים: הוספת תג
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