Understanding and drugging RAS: 40 years to break the tip of the iceberg
Several cancers and rare genetic diseases are caused by dysregulation in the RAS signaling pathway. RAS proteins serve as molecular switches that regulate pathways involved in cellular growth, differentiation and survival. These pathways have been an intense area of investigation for four decades, s...
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| Principais autores: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Company of Biologists
2022-02-01
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| Serier: | Disease Models & Mechanisms |
| Fag: | |
| Online adgang: | http://dmm.biologists.org/content/15/2/dmm049519 |
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