Aldo-keto Reductase 1B10 (AKR1B10) Suppresses Sensitivity of Ferroptosis in TNBC by Activating the AKT/GSK3β/Nrf2/GPX4 Axis

Background: Aldo-keto reductase 1B10 (AKR1B10) is expressed in various malignant tissues. Several studies have highlighted the essential function of AKR1B10 in lipid metabolism and in the detoxification of lipid peroxides. The aim of this research was to explore the role of AKR1B1...

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Autors principals: Shanli Wu, Gun Yang, Xiaosha Wen, Yi Lin, Shenglong Wang, Jing Wang, Quan Liu, Dixian Luo
Format: Artigo
Idioma:Inglês
Publicat: IMR Press 2025-06-01
Col·lecció:Frontiers in Bioscience-Landmark
Matèries:
aldo-keto reductase family 1 member b10
ferroptosis
triple-negative breast neoplasms
nfe2l2
Accés en línia:https://www.imrpress.com/journal/FBL/30/6/10.31083/FBL36615
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