iPSC screening identifies CACNA2D2 as a potential therapeutic target for FTLD-Tau

Frontotemporal Lobar Degeneration (FTLD) is a neurodegenerative disorder that affects the frontal and temporal lobes, which are crucial for regulating personality, behavior, and language. Pathologically, FTLD is characterized by Tau protein accumulation and neuronal death. In our effort to identify...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Keiko Imamura, Ayako Nagahashi, Aya Okusa, Tomoki Sakasai, Kayoko Tsukita, Yumiko Kutoku, Yutaka Ohsawa, Yoshihide Sunada, Naruhiko Sahara, Nicholas M. Kanaan, Makoto Higuchi, Kohji Mori, Manabu Ikeda, Haruhisa Inoue
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Elsevier 2025-06-01
Σειρά:	European Journal of Cell Biology
Θέματα:	Tau FTLD excitability gabapentinoids iPSCs
Διαθέσιμο Online:	http://www.sciencedirect.com/science/article/pii/S0171933525000093
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