iPSC screening identifies CACNA2D2 as a potential therapeutic target for FTLD-Tau

Frontotemporal Lobar Degeneration (FTLD) is a neurodegenerative disorder that affects the frontal and temporal lobes, which are crucial for regulating personality, behavior, and language. Pathologically, FTLD is characterized by Tau protein accumulation and neuronal death. In our effort to identify...

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Detalles Bibliográficos

Principais autores:	Keiko Imamura, Ayako Nagahashi, Aya Okusa, Tomoki Sakasai, Kayoko Tsukita, Yumiko Kutoku, Yutaka Ohsawa, Yoshihide Sunada, Naruhiko Sahara, Nicholas M. Kanaan, Makoto Higuchi, Kohji Mori, Manabu Ikeda, Haruhisa Inoue
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2025-06-01
Series:	European Journal of Cell Biology
Assuntos:	Tau FTLD excitability gabapentinoids iPSCs
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S0171933525000093
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