Adipose-specific disruption of autotaxin enhances nutritional fattening and reduces plasma lysophosphatidic acid

Autotaxin (ATX) is a secreted lysophospholipase D that generates the lipid mediator lysophosphatidic acid (LPA). ATX is secreted by adipose tissue and its expression is enhanced in obese/insulin-resistant individuals. Here, we analyzed the specific contribution of adipose-ATX to fat expansion associ...

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Detalhes bibliográficos

Principais autores:	Rodolphe Dusaulcy, Chloé Rancoule, Sandra Grès, Estelle Wanecq, André Colom, Charlotte Guigné, Laurens A. van Meeteren, Wouter H. Moolenaar, Philippe Valet, Jean Sébastien Saulnier-Blache
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2011-06-01
coleção:	Journal of Lipid Research
Assuntos:	adipocyte high-fat diet obesity
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0022227520313420
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