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The Alternating Access Mechanism in Mammalian Multidrug Resistance Transporters and Their Bacterial Homologs

Multidrug resistance (MDR) proteins belonging to the ATP-Binding Cassette (ABC) transporter group play a crucial role in the export of cytotoxic drugs across cell membranes. These proteins are particularly fascinating due to their ability to confer drug resistance, which subsequently leads to the fa...

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Bibliografiska uppgifter
Huvudupphov: Shadi A Badiee, Ugochi H. Isu, Ehsaneh Khodadadi, Mahmoud Moradi
Materialtyp: Artigo
Språk:Inglês
Utgiven: MDPI AG 2023-05-01
Serie:Membranes
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Länkar:https://www.mdpi.com/2077-0375/13/6/568
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