The Alternating Access Mechanism in Mammalian Multidrug Resistance Transporters and Their Bacterial Homologs
Multidrug resistance (MDR) proteins belonging to the ATP-Binding Cassette (ABC) transporter group play a crucial role in the export of cytotoxic drugs across cell membranes. These proteins are particularly fascinating due to their ability to confer drug resistance, which subsequently leads to the fa...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI AG
2023-05-01
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| Schriftenreihe: | Membranes |
| Schlagworte: | |
| Online-Zugang: | https://www.mdpi.com/2077-0375/13/6/568 |
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