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Effective Synthesis of mRNA during In Vitro Transcription with Fewer Impurities Produced

The remarkable efficacy of COVID-19 vaccines has established mRNA as a highly promising biomedical technology. However, the adequate application of mRNA therapeutics necessitates additional measures to mitigate the inherent immunogenicity, which is predominantly caused by dsRNA. As a byproduct of th...

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Bibliografiske detaljer
Principais autores: Wei He, Qi Geng, Guiying Ji, Ji Li, Dan Wang, Yucai He, Qiuheng Jin, Jianren Ye
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-10-01
Serier:Molecules
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Online adgang:https://www.mdpi.com/1420-3049/29/19/4713
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