Rethinking of phosphodiesterase 5 inhibition: the old, the new and the perspective in human health
The phosphodiesterases type 5 (PDE5) are catalytic enzymes converting the second messenger cyclic guanosine monophosphate (cGMP) to 5’ GMP. While intracellular cGMP reduction is associated with several detrimental effects, cGMP stabilization associates with numerous benefits. The PDE5 specific inhib...
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| Principais autores: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2024-09-01
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| Serija: | Frontiers in Endocrinology |
| Teme: | |
| Online dostop: | https://www.frontiersin.org/articles/10.3389/fendo.2024.1461642/full |
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