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A Perspective on Natural and Nature-Inspired Small Molecules Targeting Phosphodiesterase 9 (PDE9): Chances and Challenges against Neurodegeneration

As life expectancy increases, dementia affects a growing number of people worldwide. Besides current treatments, phosphodiesterase 9 (PDE9) represents an alternative target for developing innovative small molecules to contrast neurodegeneration. PDE inhibition promotes neurotransmitter release, amel...

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Bibliografische gegevens
Hoofdauteurs: Giovanni Ribaudo, Maurizio Memo, Alessandra Gianoncelli
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2021-01-01
Reeks:Pharmaceuticals
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Online toegang:https://www.mdpi.com/1424-8247/14/1/58
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