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Targeting ALK in Neuroendocrine Tumors of the Lung

BackgroundAnaplastic lymphoma kinase (ALK) rearrangements are known oncogenic drivers in non-small cell lung cancer (NSCLC). Few case reports described the occurrence of such rearrangements in large cell neuroendocrine carcinomas (LCNECs) of the lung without information on clinical responses to ALK...

Celý popis

Uloženo v:
Hlavní autoři: Dilara Akhoundova, Martina Haberecker, Ralph Fritsch, Sylvia Höller, Michael K. Kiessling, Markus Rechsteiner, Jan H. Rüschoff, Alessandra Curioni-Fontecedro
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2022-06-01
Edice:Frontiers in Oncology
Témata:
ALK rearrangements
neuroendocrine tumors of the lung
large cell neuroendocrine carcinoma
ALK inhibitors
targeted treatment
On-line přístup:https://www.frontiersin.org/articles/10.3389/fonc.2022.911294/full
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