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Targeting ALK in Neuroendocrine Tumors of the Lung

BackgroundAnaplastic lymphoma kinase (ALK) rearrangements are known oncogenic drivers in non-small cell lung cancer (NSCLC). Few case reports described the occurrence of such rearrangements in large cell neuroendocrine carcinomas (LCNECs) of the lung without information on clinical responses to ALK...

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Guardat en:
Autors principals: Dilara Akhoundova, Martina Haberecker, Ralph Fritsch, Sylvia Höller, Michael K. Kiessling, Markus Rechsteiner, Jan H. Rüschoff, Alessandra Curioni-Fontecedro
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2022-06-01
Col·lecció:Frontiers in Oncology
Matèries:
ALK rearrangements
neuroendocrine tumors of the lung
large cell neuroendocrine carcinoma
ALK inhibitors
targeted treatment
Accés en línia:https://www.frontiersin.org/articles/10.3389/fonc.2022.911294/full
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