DNAJC6 Parkinson’s disease: Endolysosomal dysfunction and emerging roles for oligodendrocytes
Abstract DNAJC6 encodes auxilin, which is predominantly expressed in neurons and oligodendrocytes. It is involved in clathrin uncoating following clathrin-mediated endocytosis (CME), and loss-of-function genetic variants have been linked to juvenile- and early-onset forms of Parkinson’s disease (PD)...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Portfolio
2026-04-01
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| Series: | npj Parkinson's Disease |
| Acceso en liña: | https://doi.org/10.1038/s41531-025-01162-1 |
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