APEX2-based proximity proteomic analysis identifies candidate interactors for Plasmodium falciparum knob-associated histidine-rich protein in infected erythrocytes

Abstract The interaction of Plasmodium falciparum—infected red blood cells (iRBCs) with the vascular endothelium plays a crucial role in malaria pathology and disease. KAHRP is an exported P. falciparum protein involved in iRBC remodelling, which is essential for the formation of protrusions or “kno...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Sébastien Charneau, Lucas Silva de Oliveira, Zenon Zenonos, Christine S. Hopp, Izabela M. D. Bastos, Damarys Loew, Bérangère Lombard, Ariane Pandolfo Silveira, Giovanna de Carvalho Nardeli Basílio Lobo, Sônia Nair Bao, Philippe Grellier, Julian C. Rayner
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Nature Portfolio 2024-05-01
Σειρά:	Scientific Reports
Θέματα:	KAHRP Protein–protein interactions APEX2 CRISPR-Cas9 Exported proteins
Διαθέσιμο Online:	https://doi.org/10.1038/s41598-024-61295-w
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