APEX2-based proximity proteomic analysis identifies candidate interactors for Plasmodium falciparum knob-associated histidine-rich protein in infected erythrocytes

Abstract The interaction of Plasmodium falciparum—infected red blood cells (iRBCs) with the vascular endothelium plays a crucial role in malaria pathology and disease. KAHRP is an exported P. falciparum protein involved in iRBC remodelling, which is essential for the formation of protrusions or “kno...

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Ngā kaituhi matua:	Sébastien Charneau, Lucas Silva de Oliveira, Zenon Zenonos, Christine S. Hopp, Izabela M. D. Bastos, Damarys Loew, Bérangère Lombard, Ariane Pandolfo Silveira, Giovanna de Carvalho Nardeli Basílio Lobo, Sônia Nair Bao, Philippe Grellier, Julian C. Rayner
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Nature Portfolio 2024-05-01
Rangatū:	Scientific Reports
Ngā marau:	KAHRP Protein–protein interactions APEX2 CRISPR-Cas9 Exported proteins
Urunga tuihono:	https://doi.org/10.1038/s41598-024-61295-w
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!