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The identification of dual protective agents against cisplatin-induced oto- and nephrotoxicity using the zebrafish model

Dose-limiting toxicities for cisplatin administration, including ototoxicity and nephrotoxicity, impact the clinical utility of this effective chemotherapy agent and lead to lifelong complications, particularly in pediatric cancer survivors. Using a two-pronged drug screen employing the zebrafish la...

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主要な著者: Jaime N Wertman, Nicole Melong, Matthew R Stoyek, Olivia Piccolo, Stewart Langley, Benno Orr, Shelby L Steele, Babak Razaghi, Jason N Berman
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications Ltd 2020-07-01
シリーズ:eLife
主題:
オンライン・アクセス:https://elifesciences.org/articles/56235
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