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Polygenic risk scores of rheumatoid arthritis associated with seropositivity and bone erosions in a Taiwanese population

Abstract Polygenic risk scores (PRS) are widely used to estimate disease risks and predict clinical outcomes. However, ethnic differences exist worldwide. We aimed to use PRS for predicting the development of rheumatoid arthritis (RA) in a Taiwanese population and investigate whether PRS of RA may b...

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Principais autores: Ting-Shuan Wu, Yen-Ju Chen, Chia-Ni Hsiung, Chien-Lin Mao, Chia-Yi Wei, I-Chieh Chen, Chung-Mao Kao, Tzu-Hung Hsiao, Wen-Nan Huang, Yi-Hsing Chen, Yi-Ming Chen
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Portfolio 2025-07-01
סדרה:Scientific Reports
נושאים:
PRS
RA
Seropositivity
Rheumatoid factor
Anti-citrullinated protein antibody
Bone erosion
גישה מקוונת:https://doi.org/10.1038/s41598-025-08254-1
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