Polygenic risk scores of rheumatoid arthritis associated with seropositivity and bone erosions in a Taiwanese population

Abstract Polygenic risk scores (PRS) are widely used to estimate disease risks and predict clinical outcomes. However, ethnic differences exist worldwide. We aimed to use PRS for predicting the development of rheumatoid arthritis (RA) in a Taiwanese population and investigate whether PRS of RA may b...

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Autori principali:	Ting-Shuan Wu, Yen-Ju Chen, Chia-Ni Hsiung, Chien-Lin Mao, Chia-Yi Wei, I-Chieh Chen, Chung-Mao Kao, Tzu-Hung Hsiao, Wen-Nan Huang, Yi-Hsing Chen, Yi-Ming Chen
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2025-07-01
Serie:	Scientific Reports
Soggetti:	PRS RA Seropositivity Rheumatoid factor Anti-citrullinated protein antibody Bone erosion
Accesso online:	https://doi.org/10.1038/s41598-025-08254-1
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