Graft-Versus-Host Disease Prevention by In Vitro-Generated Myeloid-Derived Suppressor Cells Is Exclusively Mediated by the CD11b+CD11c+ MDSC Subpopulation

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of myeloid progenitor cells that dampen overwhelming adaptive immune responses through multiple mechanisms and are recognized as an attractive novel immune intervention therapy for counteracting the destructive effects of graft-...

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Principais autores:	Jasmin Scheurer, Kerstin Kitt, Heinrich J. Huber, Katrin Fundel-Clemens, Stefan Pflanz, Klaus-Michael Debatin, Gudrun Strauss
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-10-01
coleção:	Frontiers in Immunology
Assuntos:	graft-versus-host disease prophylaxis myeloid-derived suppressor cells allogeneic bone marrow transplantation mouse model type 2 immune response
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.754316/full
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