A review of complement sources used in serum bactericidal assays for evaluating immune responses to meningococcal ACWY conjugate vaccines

Invasive meningococcal disease is rare and potentially devastating but often vaccine-preventable. Evaluation of meningococcal vaccine effectiveness is impractical owing to relatively low disease incidence; protection is therefore estimated using serum bactericidal antibody (SBA) assays. Original exp...

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Detalhes bibliográficos

Principais autores:	Jamie Findlow, Paul Balmer, Ray Borrow
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2019-10-01
Colecção:	Human Vaccines & Immunotherapeutics
Assuntos:	meningococcal vaccine neisseria meningitidis serum bactericidal antibody assay complement menacwy-tt immunogenicity
Acesso em linha:	http://dx.doi.org/10.1080/21645515.2019.1593082
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