A review of complement sources used in serum bactericidal assays for evaluating immune responses to meningococcal ACWY conjugate vaccines

Invasive meningococcal disease is rare and potentially devastating but often vaccine-preventable. Evaluation of meningococcal vaccine effectiveness is impractical owing to relatively low disease incidence; protection is therefore estimated using serum bactericidal antibody (SBA) assays. Original exp...

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Главные авторы:	Jamie Findlow, Paul Balmer, Ray Borrow
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Taylor & Francis Group 2019-10-01
Серии:	Human Vaccines & Immunotherapeutics
Предметы:	meningococcal vaccine neisseria meningitidis serum bactericidal antibody assay complement menacwy-tt immunogenicity
Online-ссылка:	http://dx.doi.org/10.1080/21645515.2019.1593082
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