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A Physiologically Based Pharmacokinetic Model to Predict Determinants of Variability in Epirubicin Exposure and Tissue Distribution

Background: Epirubicin is an anthracycline antineoplastic drug that is primarily used in combination therapies for the treatment of breast, gastric, lung and ovarian cancers and lymphomas. Epirubicin is administered intravenously (IV) over 3 to 5 min once every 21 days with dosing based on body surf...

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Autors principals: Radwan Ansaar, Robyn Meech, Andrew Rowland
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2023-04-01
Col·lecció:Pharmaceutics
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Accés en línia:https://www.mdpi.com/1999-4923/15/4/1222
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