Effects of Repeated Smoking and Quitting Cigarettes on Plasma Concentrations of Clozapine and Its N‐Desmethyl and N‐Oxide Metabolites in a Japanese Patient With Schizophrenia
ABSTRACT Clozapine (CLZ) is used for treatment‐resistant schizophrenia. However, its pharmacokinetics in Japanese patients with schizophrenia have not been well described. Smoking affects the activities of cytochrome P450 (CYP), which mainly metabolizes CLZ, and patients with schizophrenia have a hi...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Wiley
2026-06-01
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| Серии: | Neuropsychopharmacology Reports |
| Предметы: | |
| Online-ссылка: | https://doi.org/10.1002/npr2.70121 |
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