Buprenorphine Substitution as a Tapering Strategy for Opioid Discontinuation in Patients with Chronic Pain: A Nonrandomized and Proof of Concept Study

Abstract Introduction Long-term use (≥ 3 months) of opioids for chronic noncancer pain (CNCP) shows limited benefit and often leads to dependence, especially when tapered too quickly. Standard opioid discontinuation typically involves gradual dose reduction, yet many patients fail to complete it. Me...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Célian Bertin, Nicolas Kerckhove, Florent Ferrer, Bruno Pereira, Christian Duale, Damien Richard, Nicolas Authier, Noémie Delage
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Adis, Springer Healthcare 2025-10-01
Цуврал:	Pain and Therapy
Нөхцлүүд:	Buprenorphine Non-cancer chronic pain Opioid tapering Opioid use disorder Proof-of-concept Pain clinic
Онлайн хандалт:	https://doi.org/10.1007/s40122-025-00781-z
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!