Mutational Pathways and Trade-Offs Between HisA and TrpF Functions: Implications for Evolution via Gene Duplication and Divergence
When a new activity evolves by changes in a pre-existing enzyme this is likely to reduce the original activity, generating a functional trade-off. The properties of this trade-off will affect the continued evolution of both functions. If the trade-off is strong, gene duplication and subsequent diver...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
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Frontiers Media S.A.
2020-10-01
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| Serie: | Frontiers in Microbiology |
| Soggetti: | |
| Accesso online: | https://www.frontiersin.org/article/10.3389/fmicb.2020.588235/full |
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