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Cell shape and maturation impacts α-actinin-2 tension in iPSC-derived cardiomyocytes

The contractile activity of cardiomyocytes (CMs) critical to heart function emerges from the collective shortening of sarcomeres. However, how these sarcomeric forces are transmitted within CMs during this process remains poorly understood. Traction force microscopy has been used to measure overall...

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Библиографические подробности
Главные авторы: Palash K. Dutta, Joshua M. Toth, Subramanian Sundaram, Xingyu Chen, Anant Chopra, Jourdan K. Ewoldt, Paige Cloonan, Xining Gao, Andrew S. LaCroix, Brenton D. Hoffman, Vivek B. Shenoy, Christine E. Seidman, Jonathan G. Seidman, Christopher S. Chen, Jeroen Eyckmans
Формат: Artigo
Язык:Inglês
Опубликовано: AIP Publishing LLC 2026-02-01
Серии:APL Bioengineering
Online-ссылка:https://pubs.aip.org/aip/apb/article-pdf/doi/10.1063/5.0304143/20900627/016109_1_5.0304143.pdf
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