MicroRNA-124/Death-Associated Protein Kinase 1 Signaling Regulates Neuronal Apoptosis in Traumatic Brain Injury via Phosphorylating NR2B

Death-associated protein kinase 1 (DAPK1), a Ca2+/calmodulin-dependent serine/threonine-protein kinase, promotes neurons apoptosis in ischemic stroke and Alzheimer’s disease (AD). We hypothesized that knockdown DAPK1 may play a protective role in traumatic brain injury (TBI) and explore underlying m...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Yingwu Shi, Wenxing Cui, Qiang Wang, Jinpeng Zhou, Xun Wu, Jin Wang, Shenghao Zhang, Qing Hu, Liying Han, Yong Du, Shunnan Ge, Haixiao Liu, Yan Qu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2022-06-01
Schriftenreihe:	Frontiers in Cellular Neuroscience
Schlagworte:	traumatic brain injury DAPK1 miR-124 NR2B neuronal apoptosis
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fncel.2022.892197/full
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!