lncRNA XIST inhibition promotes M2 polarization of microglial and aggravates the spinal cord injury via regulating miR-124–3p / IRF1 axis

Background: Spinal cord injury (SCI) has a high disability rate and mortality rate. Recently, LncRNA XIST has been found to be involved in the regulation of inflammatory responses. Therefore, we aimed to investigate the role of XIST in the occurrence and development of SCI and the specific regulatio...

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Hlavní autoři:	Jin Yang, Zhiqiang Gong, Junjie Dong, Hangchuan Bi, Bing Wang, Kaili Du, Chunqiang Zhang, Lingqiang Chen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2023-07-01
Edice:	Heliyon
Témata:	lncRNA XIST Spinal cord injury Microglia Polarization miR-124–3p IRF1
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2405844023050600
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