Infection of RANKL-primed RAW-D macrophages with Porphyromonas gingivalis promotes osteoclastogenesis in a TNF-α-independent manner.

Infection of macrophages with bacteria induces the production of pro-inflammatory cytokines including TNF-α. TNF-α directly stimulates osteoclast differentiation from bone marrow macrophages in vitro as well as indirectly via osteoblasts. Recently, it was reported that bacterial components such as L...

Descripción completa

Detalles Bibliográficos

Autores principales:	Akiko Kukita, Yuka Ichigi, Ippei Takigawa, Toshiyuki Watanabe, Toshio Kukita, Hiroshi Miyamoto
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Public Library of Science (PLoS) 2012-01-01
Colección:	PLoS ONE
Acceso en línea:	http://europepmc.org/articles/PMC3377672?pdf=render
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!