Infection of RANKL-primed RAW-D macrophages with Porphyromonas gingivalis promotes osteoclastogenesis in a TNF-α-independent manner.

Infection of macrophages with bacteria induces the production of pro-inflammatory cytokines including TNF-α. TNF-α directly stimulates osteoclast differentiation from bone marrow macrophages in vitro as well as indirectly via osteoblasts. Recently, it was reported that bacterial components such as L...

Descripció completa

Dades bibliogràfiques

Autors principals:	Akiko Kukita, Yuka Ichigi, Ippei Takigawa, Toshiyuki Watanabe, Toshio Kukita, Hiroshi Miyamoto
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2012-01-01
Col·lecció:	PLoS ONE
Accés en línia:	http://europepmc.org/articles/PMC3377672?pdf=render
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!