TP53 mutations as drivers of chordoma progression and hallmarks of aggressive chordoma
Abstract Introduction Dedifferentiated (DC) and poorly differentiated chordomas (PDC) are rare, aggressive chordomas with a significantly worse prognosis than conventional chordomas (CC). The molecular mechanisms driving them remain poorly understood. Methods Matched primary CC and recurrent DC cryo...
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| Автори: | , , , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
BMC
2025-12-01
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| Серія: | Acta Neuropathologica Communications |
| Предмети: | |
| Онлайн доступ: | https://doi.org/10.1186/s40478-025-02180-z |
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