QR kód

TP53 mutations as drivers of chordoma progression and hallmarks of aggressive chordoma

Abstract Introduction Dedifferentiated (DC) and poorly differentiated chordomas (PDC) are rare, aggressive chordomas with a significantly worse prognosis than conventional chordomas (CC). The molecular mechanisms driving them remain poorly understood. Methods Matched primary CC and recurrent DC cryo...

Celý popis

Uloženo v:
Hlavní autoři: Szymon Baluszek, Paulina Kober, Michał Wa̧grodzki, Jacek Kunicki, Bartosz Wojtaś, Paulina Szadkowska, Bożena Kamińska, Thibault Passeri, Tomasz Mandat, Mateusz Bujko
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2025-12-01
Edice:Acta Neuropathologica Communications
Témata:
Chordoma
TP53
DNA sequencing
Dedifferentiated chordoma
Poorly differentiated chordoma
On-line přístup:https://doi.org/10.1186/s40478-025-02180-z
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Podobné jednotky