Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity
<p>Abstract</p> <p>α-synuclein (α-syn) is a main component of Lewy bodies (LB) that occur in many neurodegenerative diseases, including Parkinson's disease (PD), dementia with LB (DLB) and multi-system atrophy. α-syn mutations or amplifications are responsible for a subset of autosomal dominant fami...
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| Principais autores: | , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2008-11-01
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| coleção: | Molecular Brain |
| Acesso em linha: | http://www.molecularbrain.com/content/1/1/17 |
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