क्यूआर कोड

Pharmacokinetic Interaction Between Olaparib and Regorafenib in an Animal Model

Background: Olaparib (OLA) and regorafenib (REG) are metabolized by the CYP3A4 isoenzyme of cytochrome P450. Both drugs are also substrates and inhibitors of the membrane transporters P-glycoprotein and BCRP. Therefore, the potential concomitant use of OLA and REG may result in clinically relevant d...

पूर्ण विवरण

में बचाया:
मुख्य लेखकों: Danuta Szkutnik-Fiedler, Agnieszka Karbownik, Filip Otto, Julia Maciejewska, Alicja Kuźnik, Tomasz Grabowski, Anna Wolc, Edmund Grześkowiak, Joanna Stanisławiak-Rudowicz, Edyta Szałek
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI AG 2024-12-01
श्रृंखला:Pharmaceutics
विषय:
drug–drug interaction
pharmacokinetics
olaparib
regorafenib
rats
ऑनलाइन पहुंच:https://www.mdpi.com/1999-4923/16/12/1575
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