Caloric Restriction Mimetic 2-Deoxyglucose Reduces Inflammatory Signaling in Human Astrocytes: Implications for Therapeutic Strategies Targeting Neurodegenerative Diseases

Therapeutic interventions are greatly needed for age-related neurodegenerative diseases. Astrocytes regulate many aspects of neuronal function including bioenergetics and synaptic transmission. Reactive astrocytes are implicated in neurodegenerative diseases due to their pro-inflammatory phenotype c...

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Hlavní autoři:	Kaylie-Anna Juliette Vallee, Jerel Adam Fields
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2022-02-01
Edice:	Brain Sciences
Témata:	neurodegenerative disease caloric restriction glycolysis astrogliosis inflammation immunometabolism
On-line přístup:	https://www.mdpi.com/2076-3425/12/3/308
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