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Exploring the binding dynamics of anticancer Dihydropyrimidinone derivatives with Serum Albumin: A multispectral approach

In this work, we have investigated the synthesis and characterization of two novel anticancer agents, 5-acetyl-6-methyl-4-phenyl-3,4-dihydropyrimidin-2(1H)-one (L1) and 2-Acetyl-4-(3,4-dimethoxy-phenyl)-6-methyl-3,4-dihydro-1H-pyrimidin-2-one (L2), utilizing the Biginelli reaction, which involves th...

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Principais autores: Chandraprakash Gond, Shivani Daksh, Akanksha Mishra, Nikhil Kumar, Anupama Datta, Anjani Kumar Tiwari
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2025-06-01
coleção:Chemical Physics Impact
Assuntos:
BSA
ADMET
Docking
Biginelli reaction
Photophysical
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2667022425000398
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