Therapeutic stapled peptides: Efficacy and molecular targets
Peptide stapling, by employing a stable, preformed alpha-helical conformation, results in the production of peptides with improved membrane permeability and enhanced proteolytic stability, compared to the original peptides, and provides an effective solution to accelerate the rapid development of pe...
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| Principais autores: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2024-05-01
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| Serier: | Pharmacological Research |
| Fag: | |
| Online adgang: | http://www.sciencedirect.com/science/article/pii/S1043661824000811 |
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