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Therapeutic stapled peptides: Efficacy and molecular targets

Peptide stapling, by employing a stable, preformed alpha-helical conformation, results in the production of peptides with improved membrane permeability and enhanced proteolytic stability, compared to the original peptides, and provides an effective solution to accelerate the rapid development of pe...

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Autori principali: Yulei Li, Minghao Wu, Yinxue Fu, Jingwen Xue, Fei Yuan, Tianci Qu, Anastassia N. Rissanou, Yilin Wang, Xiang Li, Honggang Hu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2024-05-01
Serie:Pharmacological Research
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Accesso online:http://www.sciencedirect.com/science/article/pii/S1043661824000811
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