Rare variants at KCNJ2 are associated with LDL-cholesterol levels in a cross-population study

Abstract Leveraging whole genome sequencing data of 1751 individuals from the UK and 2587 Qatari subjects, we suggest here an association of rare variants mapping to the sour taste-associated gene KCNJ2 with reduced low-density lipoprotein cholesterol (LDL-C, P = 2.10 × 10−12) and with a 22% decreas...

Descripció completa

Dades bibliogràfiques

Autors principals:	Niccolò Rossi, Najeeb Syed, Alessia Visconti, Elbay Aliyev, Sarah Berry, Mafalda Bourbon, Tim D. Spector, Pirro G. Hysi, Khalid A. Fakhro, Mario Falchi
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2024-06-01
Col·lecció:	npj Genomic Medicine
Accés en línia:	https://doi.org/10.1038/s41525-024-00417-9
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!