Rare variants at KCNJ2 are associated with LDL-cholesterol levels in a cross-population study
Abstract Leveraging whole genome sequencing data of 1751 individuals from the UK and 2587 Qatari subjects, we suggest here an association of rare variants mapping to the sour taste-associated gene KCNJ2 with reduced low-density lipoprotein cholesterol (LDL-C, P = 2.10 × 10−12) and with a 22% decreas...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Portfolio
2024-06-01
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| Schriftenreihe: | npj Genomic Medicine |
| Online-Zugang: | https://doi.org/10.1038/s41525-024-00417-9 |
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