DNA demethylating agents suppress preclinical models of synovial sarcoma
Synovial sarcoma is an aggressive soft-tissue cancer driven by the chimeric SS18::SSX fusion oncoprotein, which disrupts chromatin remodeling by combining two antagonistic transcriptional regulators. SS18 participates in BAF complexes that open chromatin, while the SSX genes are cancer-testis antige...
Gorde:
| Egile Nagusiak: | , , , , , , , , , , , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society for Clinical Investigation
2025-07-01
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| Saila: | The Journal of Clinical Investigation |
| Gaiak: | |
| Sarrera elektronikoa: | https://doi.org/10.1172/JCI190855 |
| Etiketak: |
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